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The usual oral adult dose of Azithromycin is 500 mg as a single dose daily for 3 days. Alternatively, an initial dose of 500 mg may be followed by 250 mg daily for a further 4 days.
For uncomplicated genital infections caused by Chlamydia trachomatis and chancroid, 1 g of Azithromycin is given as a single dose. A single dose 2 g has been given for uncomplicated gonorrhea.
For the treatment of granuloma inguinale, an initial dose of 1 g followed by 500 mg daily may be given, or 1 g may be given once a week for at least 3 weeks, until all lesions have completely healed.
For prophylaxis of disseminated MAC infections, Azithromycin 1.2 g may begiven once weekly.
For treatment or secondary prophylaxis, 500 mg once daily should be given with other antimycobacterials.
For mild or moderate typhoid caused by multidrug-resistant strains, 500 mg once daily may be given for 7 days.
